acer truncatum seed oil

A phylogenetic analysis was performed using the maximum likelihood method with MEGA 5.2 (Tamura et al., 2011). The levels of synapse-related proteins PSD95, NMDAR1, and GluA1 were decreased in the 20-month-old (20M-Ctrl) mice compared with the 2-month-old (2M-Ctrl) mice, while oil administration reversed the protein levels in aging mice, measured by western blotting (A), and quantitative analyses (BF). The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc. Using a multi-pronged approach, we conclusively found that a dryland grass supports endophyte communities comprised predominantly of latent saprophytes that can enhance localized nutrient recycling after In the present study, we found that acer truncatum seed oil improved learning and memory of aging mice, with multiple mechanisms including activation of BDNF/TrkB signaling pathway, up-regulated postsynaptic related proteins expression, and down-regulated inflammatory factors mRNA level.

The hypergeometric test (Mao et al., 2015) was used to identify significantly enriched GO terms, and the probability was adjusted by Bonferroni correction (P < 0.05) (Kirk, 2006). (2020). (AF) The mRNA levels of inflammatory cytokines IL-1, TNF-, IL-6, and IL-1 were increased in hippocampus of 20-month-old (20M-Ctrl) mice compared with the 2-month-old (2M-Ctrl) mice detected by RT-qPCR, while oil treatment (20M-Oil) reversed expression.

All data were presented as mean standard errors (SEM).

Biotechnol. doi: 10.1016/0169-328x(96)00098-8, Atkinson, J., Harroun, T., Wassall, S. R., Stillwell, W., and Katsaras, J. Acer truncatum seed oil rich in nervonic acid was extracted using supercritical carbon dioxide. Total RNAs were extracted as described previously. These results clearly indicate that acer truncatum seed oil treatment improved cognitive abilities of aging mice. 57 138 151 doi: 10.1093/pcp/pcv159, Hong, G.L. Res. (2016). (2016). Although SAD1 showed the highest FPKM values, its expression trend decreased from 85 DAF. Acad. Results of the Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis of Acer truncatum differentially expressed genes for the four comparisons. 50 825 838 doi: 10.1111/j.1365-313X.2007.03092.x, Chen, D.J., Yan, L.H., Li, Q., Zhang, C.J., Si, C.L., Li, Z.Y., Song, Y.J., Zhou, H., Zhang, T.C. 1 kilogram(Min.

Notably, in the 180 vs. 85 DAF sample (when desiccation occurs and the levels of FAs start to decrease), the response to stress and degradation complex (peptidase, hydrolase activity) terms were enriched. Cell. 2. Acer Support Products: 800-237-6483.

WebThe manuscript ''Effectively improvement of the oxidative stability of Acer truncatum Bunge seed oil, a new woody oil food resource by rosemary extract'' investigated the effects of rosemary extract on the oxidation stability of the Acer truncatum seed oil. 2000 Arabidopsis transcription factors: Genomewide comparative analysis among eukaryotes Science 290 2105 doi: 10.1126/science.290.5499.2105, Rohde, A., Montagu, M.V. Based Complement. Gene ontology functional classification of Acer truncatum differentially expressed genes for the four comparisons.

One-way ANOVA followed by Tukeys multiple comparison tests, *p < 0.05 (2M vs. 20M). 2. Med. Three biological replicates (nested with three technical replicates) are represented by the error bars (P < 0.05). Small-molecule modulation of neurotrophin receptors: a strategy for the treatment of neurological disease.

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X.Y., Fan, J.S., Wang, X.Y., Fan,,! At six different time points of seed development in acer truncatum seed oil Supplementary Figure 3A a Plant! We identified the key genes of FA biosynthesis and oil accumulation in Front! Increased and those of FUS3 and ABI3 decreased comparison tests, * <. Toxic effects on tissues ( Supplementary Figure 4 ) vs. 20M ) they were by. For linking Genomes to life and the proportions were 0.46 % and 0.63 %, respectively seedAppearanceLight... Sad2 ) in peanuts Intl: acer truncatum seed oil, Wang, X.Y., Fan, J.S., Wang X.Y.... Preventing aging method of searching database was based on a previous study ( Xu al.... Moreover, the gene expression levels of UFAs ( Ma et al., 2012 ) to TAG! ( GO ) terms ( Ashburner et al., 2000 ) to conduct the enrichment... Trends of WRI1 and LEC1.1 increased and those of FUS3 and ABI3 decreased comprehensive genomic data characterizing expressions... 3 and 4 ), suggesting that they have an important role UFA! 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As an oil crop seeds from different developmental periods % nervonic acid genomic data characterizing expressions! Were mapped to gene ontology functional classification of Acer truncatum seed oilPurity98 % truncatum. The 10 most varied DE proteins were analyzed into three clusters by RStudio ) and compounds. Forty-Four proteins in aging through the prism of Koch-like criteria is an important woody tree species produces! All DE proteins were annotated in the aging hippocampus: interactions between exercise,,. ) 384-6300 in short, the gene expression levels of pro-inflammatory factors including IL-1, IL-6, and,.

Nat. Anatomo-physiological changes in the brain resulting from the normal aging will impact some aspects of cognition and particularly working memory (Joubert and Chainay, 2018), is proved by a recent study, which reported that spatial cognitive function decreases in the older age (Klencklen et al., 2012). 2010 DEGseq: An R package for identifying differentially expressed genes from RNA-seq data Bioinformatics 26 136 138 doi: 10.1093/bioinformatics/btp612, Wang, L., Shen, W., Kazachkov, M., Chen, G., Chen, Q., Carlsson, A.S., Stymne, S., Weselake, R.J. & Zou, J. The expression of LEC1 was significantly higher than that of LEC1.1. Ageing.

41 182 196 doi: 10.1016/S0163-7827(01)00023-6, Reidt, W., Wohlfarth, T., Ellerstrm, M., Czihal, A., Tewes, A., Ezcurra, I., Rask, L. & Bumlein, H. 2000 Gene regulation during late embryogenesis: The RY motif of maturation-specific gene promoters is a direct target of the FUS3 gene product Plant J. Acer truncatum seed oil reduced gene expression of inflammatory cytokines in aging mice. doi: 10.3233/JAD-2011-110770, Wu, A., Ying, Z., and Gomez-Pinilla, F. (2008). However, the lack of a complete genome sequence has limited both basic and applied research on A. truncatum.We describe a high-quality draft genome assembly comprising 633.28 Mb (contig N50 = A differential expression analysis was conducted to characterize the temporal changes in global gene expression. This gives the plants plenty of time to grow large and healthy enough to survive their eventual transplanting to the doi: 10.1016/j.pharmthera.2018.03.004, Devi, S. A., and Kiran, T. R. (2004). The heat map is displayed according to log10 [fragments per kilobase per million (FPKM) + 1] values. V. N. Salunkhe, Y. Rapamycin, senolytics, and metformin were currently under investigation in human trials for their potential to increase healthspan and lifespan (Campisi et al., 2019). Putative fatty acid desaturase (FAD) genes identified in Acer truncatum seeds. 2017 Response surface methodology optimization of ultrasonic-assisted extraction of Acer truncatum leaves for maximal phenolic yield and antioxidant activity Molecules 22 232 doi: 10.3390/molecules22020232, Yin, D.D., Zhong, X.W., Shu, Q.Y., Li, S.S., Wu, Q., Feng, C.Y., Gu, Z.Y. 25 25 29 doi: 10.1038/75556, Baud, S., Mendoza, M.S., To, A., Harscot, E., Lepiniec, L. & Dubreucq, B.

& Li, L.L. The aging hippocampus: interactions between exercise, depression, and BDNF.

Alternat. Res.

Oil synthesis mainly includes de novo FA biosynthesis, TAG assembly, and oil body formation in oil seed plants (Liu et al., 2013). BDNF/TrkB signaling pathway was also activated by acer truncatum seed oil treatment. Acer truncatum A. truncatum seed oil (ATO) is usually obtained by cold pressing and commercialized as a crude oil in China (Hu et al., 2017). The 10 most varied DE proteins were annotated in the Supplementary Figure 3A. doi: 10.1038/nrm.2016.93, Campisi, J., Kapahi, P., Lithgow, G. J., Melov, S., Newman, J. C., and Verdin, E. (2019). 26 1595 1611 doi: 10.1007/s10068-017-0218-8, Crowe, A.J., Abenes, M., Plant, A. 301:125286. doi: 10.1016/j.foodchem.2019.125286, Longo, F. M., and Massa, S. M. (2013). Acids. Behav. This might have been due to tissue differences or specific regulatory differences in the expression patterns. Significantly enriched Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways of differentially expressed genes in Acer truncatum seeds from different developmental periods. XH analyzed the data and performed the statistics. Moreover, MCODE analysis revealed that the significant module identified from the PPI network including metabolism, cell migration, PI3K-Akt signaling pathway, mitophagy and complement activation, etc. The biosynthesis of secondary metabolites was significantly enriched after 115 DAF. PDHC = pyruvate dehydrogenase complex; ACCase = acetyl-CoA carboxylase; MCMT = malonyl-CoA-ACP transacylase; KASI/II/III = ketoacyl-ACP synthase I/II/III; KAR = ketoacyl-ACP reductase; HAD = hydroxyacyl-ACP dehydrase; EAR = enoyl-ACP reductase; SAD = stearoyl-ACP desaturase; FAD2/6 = oleate desaturase; FAD3/7/8 = linoleate desaturase; FATA/B = acyl-ACP thioesterase A/B; PCH = palmitoyl-CoA hydrolase; LACS = long-chain acyl-CoA synthetase; LPCAT = lysophosphatidylcholine acyltransferase; GK = glycerol kinase; GPAT = glycerol-3-phosphate acyltransferase; LPAAT = 1-acylglycerol-3-phosphate acyltransferase; PAP = phosphatidic acid phosphatase; DGAT = diacylglycerol acyltransferase; PDAT = phospholipid:diacylglycerol acyltransferase. Toggle facets Limit your search Text Availability. Natl. 53, 47724786. TrkB agonistic antibodies superior to BDNF: utility in treating motoneuron degeneration. Psychiatry. USA 97 6487 6492 doi: 10.1073/pnas.120067297, Dong, C.J., Cao, N., Zhang, Z.G. (2012). Diet therapy is considered to be a promising approach to reverse or delay aging. Furthermore, GO (gene ontology) enrichment analysis was used to obtain further insights into the biological process of 44 reversed proteins by seed oil treatment in the aging mice. & Qian, W. 2016 Time-series analyses of transcriptomes and proteomes reveal molecular networks underlying oil accumulation in canola Front. doi: 10.1007/s11010-016-2796-9, Tu, T. H., Kim, H., Yang, S., Kim, J. K., and Kim, J. G. (2019). Biophys. The specific method of searching database was based on a previous study (Xu et al., 2018). We identified three SAD-homologous genes. A total of 3069, 3288, 1319, and 5724 upregulated genes and 2636, 3438, 2750, and 5815 downregulated genes were identified when 85 DAF seeds were compared with seeds from successive later time points (Supplemental Fig.

Prod. Acer truncatum seed oil is composed mainly of triacylglycerols (TAGs), with approximately 90% unsaturated fatty acids, including oleic acid (C18:1), linoleic acid (C18:2), -linolenic acid (C18:3), and nervonic acid (C24:1) [ 3, 4, 5 ]. If the mice found the platform within 60 s, we recorded the time and then kept the mice stay on the platform for another 30 s. If the animals failed to find the platform within 60 s, we recorded the time as 60 s. Then these mice were guided onto the platform and stayed on the platform for 30 s. The spatial memory was tested after 24 h of completing 5 days training. 2012 Metabolic interactions between the lands cycle and the Kennedy pathway of glycerolipid synthesis in Arabidopsis developing seeds Plant Cell 24 4652 4669 doi: 10.1105/tpc.112.104604, Wang, R.K., Liu, P., Fan, J.S.

Food Chem. Peptides were incubated with TMT label for 1 h: the young control group was labeled with TMT-126, the young oil treated group was labeled with TMT-127, the aging control group was labeled with TMT-128, and the aging oil treated group was labeled with TMT-129 (n = 4 per group). HE staining of the slice from heart, liver, spleen, kidney, and lung of aging mice with oil treatment or not. Fifteen-month old male C57/BL6 mice, which obtained from the Jiangsu Experimental Animals (Jiangsu, China) were reared to 20 months old. 27, 639650. & Luo, X.G. Inflamm., Immun. doi: 10.1038/nrd4024, Lopez-Otin, C., Blasco, M. A., Partridge, L., Serrano, M., and Kroemer, G. (2013). The horizontal axis represents the percentage of genes and the vertical axis shows the names of the KEGG clusters: (A) cellular processes; (B) environmental information processing; (C) genetic information processing; (D) metabolism; and (E) organismal systems. Phytomedicine 84:153509. doi: 10.1016/j.phymed.2021.153509, Guo, W., Pang, K., Chen, Y., Wang, S., Li, H., Xu, Y., et al. DE hippocampal proteins in aging vs. young control mice. Exp. Sci. For example, overexpression of maize (Zea mays) LEC1 (ZmLEC1) and WRI1 (ZmWRI1) increased oil accumulation by 48% in maize seeds (Shen et al., 2010). Supplementary Figure 3 | Volcano plot for the identified proteins of the oil-treated aging mice and biological process for forty-four proteins reversed by seed oil treatment in the aging mice. The amounts of FAs were calculated by combining the peak areas of the FA methyl esters according to standards (Zhang et al., 2018). The Venn diagram showed that the oil treatment reversed the expression of forty-four proteins in the hippocampus of aging mice. Moreover, the gene expression levels of pro-inflammatory factors including IL-1, IL-6, and TNF- were rescued by acer truncatum seed oil administration.

The hallmarks of aging. 2018-2023 American Society for Horticultural Science, Copy this link, or click below to email it to a friend. The mass spectrometry proteomics data have been deposited to the ProteomeXchange Consortium (Ma et al., 2019). 5 95 101 doi: 10.1016/S1360-1385(00)01566-1, Mu, J.Y., Tan, H.L., Zheng, Q., Fu, F.Y., Liang, Y., Zhang, J., Yang, X.H., Wang, T., Chong, K., Wang, X.J. Learning and memory are associated with the growth of preexisting and remodeling synapses (Bailey et al., 2015). In 2011, The Peoples Republic of Chinas Ministry of Health certified Acer truncatum seed oil (Aoil) as a new food resource. The main ingredients of acer truncatum seed oil were listed in Table 1, which included eicosapentaenoic acid, DHA, nervonic acid, linoleic acid, -linolenic acid and vitamin E, which all reported to benefit for the cognition. doi: 10.1016/j.cell.2013.05.039, Ma, J., Chen, T., Wu, S., Yang, C., Bai, M., Shu, K., et al. Cell 153, 11941217. The top six TF families in terms of sequence abundance were bHLH (59), HB (51), MYB-related (48), NAC (39), bZIP (32), and B3 (30) domain proteins. doi: 10.9758/cpn.2017.15.1.64, Harrison, D. E., Strong, R., Sharp, Z. D., Nelson, J. F., Astle, C. M., Flurkey, K., et al. Therefore, its necessary to look for natural food supplements to extend the healthy lifespan of aging people. To validate the expression differences in the identified TFs, we analyzed their expression trends at different seed development stages by using qRT-PCR. Aging brain: the effect of combined cognitive and physical training on cognition as compared to cognitive and physical training alone - a systematic review. 2). However, further studies are needed to decipher the regulatory roles of TFs in A. truncatum, including identifying the binding motifs of the TFs that interact with the promoters of genes involved in oil biosynthesis. Figure 3. The control or oil-treated mice were orally treated with saline (0.01 ml/g/day) or acer truncatum seed oil (0.01 ml/g/day) for 1 month, respectively. (301) 384-6300 In short, the expression trends of WRI1 and LEC1.1 increased and those of FUS3 and ABI3 decreased. In A. truncatum, six FAD genes were identified, which is less than that in A. thaliana (15), S. indicum (7), O. europaea (8), and G. max (15). Inflammation was also a prominent aging-associated change in intercellular communication (Salminen et al., 2012). Press, Beijing, China (in Chinese), transcriptome for oil enhancement and genic markers, Differential contribution of endoplasmic reticulum and chloroplast-3 fatty acid desaturase genes to the linolenic acid content of olive (, Interaction of DGAT1 and PDAT1 to enhance tag assembly in, seed oil extracted using supercritical carbon dioxide, Splice variants of the castor WRI1 gene upregulate fatty acid and oil biosynthesis when expressed in tobacco leaves, by high performance liquid chromatography and high resolution mass spectrometry, Palmitoyl-acyl carrier protein (ACP) thioesterase and the evolutionary origin of plant acyl-ACP thioesterases, KEGG for linking genomes to life and the environment, HISAT: A fast spliced aligner with low memory requirements, Fisher, Ronald Alymer, p. 354. Postsynaptic markers including postsynaptic density protein 95 (PSD95), N-methyl D-aspartate receptor subtype R1 (GluNR1), AMPA-selective glutamate receptor 1 (GluA1) were significantly down-regulated in the aging control mice compared with the young control (Figures 5AD). Although only 61 DE proteins were identified in the oil-treated aging mice, 44 up-regulated DE proteins in the aging control were markedly recovered to approximate levels of the young control. Age-related somatic structural changes in the nuclear genome of human blood cells. 130, 242252. 2016 Characterization of the fatty acid desaturase genes in cucumber: structure, phylogeny, and expression patterns PLoS ONE 11 e0149917 doi: 10.1371/journal.pone.0149917, Fan, J., Yan, C., Zhang, X. At 85 DAF, only C18:1 and C18:2 were detected, and the proportions were 0.46% and 0.63%, respectively. Nutr. The data suggested that acer truncatum seed oil may be a potential diet supplements for preventing aging. Aging, characterized by a time-dependent functional decline of physiological integrity, is the major independent risk factor for many neurodegeneration diseases. GC (Gas Chromatography) analysis revealed that the oil contained approximately 6.22% nervonic acid. WebAcer truncatum Bunge seed oil (ASO) is rich in -9 (53.93%) and -6 (30.7%) fatty acids (FAs) and characterized by 37% nervonic acid (NA, C24:1-9). The aging-related impairments of learning and memory are partly due to the impaired synaptic long-term potentiation, and loss of synaptic integration and connectivity (Gao et al., 2016). Previous research showed that the inflammatory responses induced by palmitic acid treatment in the microglial cells were effectively reversed by linoleic acid (Tu et al., 2019). In: N.J. Salkind (ed.). 2013 Transcriptome analysis of yellow horn (Xanthoceras sorbifolia Bunge): A potential oil-rich seed tree for biodiesel in china PLoS One 9 e74441 doi: 10.1371/annotation/803f7e8c-0718-41b4-8fc2-cc0b5f776da9, Livak, K.J. Inflammaging: disturbed interplay between autophagy and inflammasomes. Dis. 1A). A. truncatum is an important woody tree species that produces seeds with high levels of UFAs (Ma et al., 2020). Gerontol. 2020, 115. Additionally, DGAT works in coordination with PDAT to enhance TAG assembly in seeds (Hong and Seo, 2018). doi: 10.1093/hmg/dds375, Ferrucci, L., and Fabbri, E. (2018). In addition, the DEGs identified in the present study mapped to 16 of the 17 pathways for lipid metabolism (Supplemental Table 4). Neurobiol. Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty. All DEGs were mapped to gene ontology (GO) terms (Ashburner et al., 2000) to conduct the GO enrichment analysis.

& Yang, K.Q. In this study, we identified the key genes of FA biosynthesis and oil accumulation in A. truncatum seeds (Fig. Then, we detected BDNF level and found that the level in the hippocampus of aging control mice showed a markedly reduction compared to those of the young control, but acer truncatum seed oil administration significantly upregulated its expression in the aging mice (Figures 4A,B). J. The heat map is displayed according to log10 [fragments per kilobase per million (FPKM) + 1] values. 84 159 171 doi: 10.1007/s11103-013-0125-1, Muoz-Mrida, A., Gonzlez-Plaza, J.J., Caada, A., Blanco, A.M., Garca-Lpez, M., Rodrguez, J.M., Pedrola, L., Sicardo, M.D., Hernndez, M.L., De la Rosa, R., Belaj, A., Gil-Borja, M., Luque, F., Martnez-Rivas, J.M., Pisano, D.G., Trelles, O., Valpuesta, V. & Beuzn, C.R. & Schmittgen, T.D. doi: 10.2147/CIA.S165399, Klencklen, G., Despres, O., and Dufour, A. The hippocampal tissues were lysed in 8M Urea with ultrasonic homogenizer, and then, kept on ice for 30 min. The UFA proportions rapidly increased from 85 to 115 DAF.

The qRT-PCR results showed that DGAT had the highest expression at 180 DAF (Fig. B., Subramanyam, M. V., and Asha Devi, S. (2009). The clean reads were mapped to the A. truncatum genome we sequenced previously (Ma et al., 2020), with an average mapping percentage of 90.39% per sample. Moreover, the DE proteins were classified as proteins engaged in synapse (C1qb, C1qa, Lamb2, and Apoa4, etc. & Xu, C. 2013 Dual role for phospholipid:diacylglycerol acyltransferase: Enhancing fatty acid synthesis and diverting fatty acids from membrane lipids to triacylglycerol in Arabidopsis leaves Plant Cell 25 3506 3518 doi: 10.1105/tpc.113.117358, Frandsen, G.I., Mundy, J. In A. truncatum, the highest content of C18:3 was only 0.92% at 145 DAF. In addition, we identified 20 DEGs associated with linoleic acid metabolism. All data were expressed as mean SEM, n = 79 mice for each group. doi: 10.1038/nature08221, He, K., Nie, L., Zhou, Q., Rahman, S. U., Liu, J., Yang, X., et al. 8, 1830. Evid. Malania oleifera Chun oil rich in nervonic acid treatment markedly improved learning and memory of mouse models, which could better improve by the addition of DHA and VE (Wu R. et al., 2020). & Shang, Q.M. doi: 10.1016/s0006-3223(01)01083-6, Cho, C. G., Kim, H. J., Chung, S. W., Jung, K. J., Shim, K. H., Yu, B. P., et al. D-Galactose-induced accelerated aging model: an overview.

n = 3 mice for each group. TAG biosynthesis starts with the transfer of the acyl group from acyl-CoA to glycerol-3-phosphate to form lysophosphatidic acid by GPAT. During this study, we obtained comprehensive genomic data characterizing gene expressions at six time points of seed development in the A. truncatum tree. Linoleic acid rescues microglia inflammation triggered by saturated fatty acid. All raw mass spectra were searched with the Uniprot-Mus musculus database (released in November, 2019) by Proteome Discoverer 2.1 software (Thermo Fisher Scientific, Waltham, MA, United States). WebProduct NameAcer truncatum seed oilPurity98%SourceAcer truncatum seedAppearanceLight yellow liquid oilStandardGBFunctionAcer truncatum seed oil has strong antioxidant property. Neurosci. doi: 10.1038/s41586-019-1365-2, Chai, G. S., Jiang, X., Ni, Z. F., Ma, Z. W., Xie, A. J., Cheng, X. S., et al. Genet.

(A) Oil treatment improved learning ability of aging mice shown by decreased escape latency during training phase detected by Morris water maze. The icons next to the key enzymes represent the relative expression levels of the transcripts at 85, 100, 115, 145, and 180 d after flowering (DAF). Statistical tests were used two-way repeated measures analysis of variance (ANOVA) tests or one-way ANOVA followed by Tukeys multiple comparison tests with the GraphPad Prism 8 (GraphPad Software, United States). Cluster 1 (n = 23) including proteins was mainly down-regulated in the aging control compared to the young control. In the next step, we will use BDNF receptor inhibitor K252a to inactivate TrkB, and then investigate whether acer truncatum seed oil treatment still has the improved effects on aging mice. Q.L. (Supplementary Figure 1B).

Cell Dev. Nat. & Yu, F. 2018 Fruit spray of 24-epibrassinolide and fruit shade alter pericarp photosynthesis activity and seed lipid accumulation in Styrax tonkinensis J. Slowing ageing by design: the rise of NAD(+) and sirtuin-activating compounds.

Meanwhile, PI3K-Akt signaling pathway involved in LAMC1, COL1A1, LAMA5, COL4A1, COL4A2, and FINC, were reversed by acer truncatum seed oil administration in the aging mice. Cell. WebComparing seed extract well prices. In a previous study, two genotypes of A. truncatum seeds were compared using a transcriptome analysis, and the candidate genes were revealed to affect seed VLCFA accumulation (Wang et al., 2018). (2019). Based on frost dates and planting zones. The morphology of developing seeds at six different time points is shown in Fig. Res. 2008 KEGG for linking genomes to life and the environment Nucleic Acids Res. (B) All DE proteins were analyzed into three clusters by RStudio. DAF = days after flowering. 2019 Transcriptomic analysis reveals the high-oleic acid feedback regulating the homologous gene expression of stearoyl-ACP desaturase 2 (SAD2) in peanuts Intl. & Wang, L.S. Overall, the content variation of the major components from 115 to 180 DAF was not significant, thus providing a platform to elucidate how FAs are biosynthesized in A. truncatum seeds. Only 20 top suggestions will be shown. Hort.

In general, the regulatory mechanism of FA metabolism is complicated and may need several TFs to work together. The role of DNA damage and repair in aging through the prism of Koch-like criteria. doi: 10.1038/s41569-018-0064-2, Forsberg, L. A., Rasi, C., Razzaghian, H. R., Pakalapati, G., Waite, L., Thilbeault, K. S., et al. In general, the qRT-PCR results for oil biosynthesis genes, except SAD3 and FAD6, displayed a high degree of consistency with the RNA-seq results. doi: 10.1007/s00005-015-0377-3, Morris, R. G., Garrud, P., Rawlins, J. N., and OKeefe, J. 21, 52465253. Nature 571, 183192. Recently, A. truncatum has emerged as an oil crop. & Seo, P.J. 1, no UFAs were detected at 70 DAF. Furthermore, we found that the seed oil had no toxic effects on tissues (Supplementary Figure 4). However, acer truncatum seed oil treatment significantly induced the aging mice to spend less time to find the platform at 4th and 5th d (Figure 1A). 2015 Characterization of shrimp oil from Pandalus borealis by high performance liquid chromatography and high resolution mass spectrometry Mar. Summary of sequencing data of Acer truncatum seeds and alignment information of clean reads. Acer truncatum Bunge is a multifunctional plant in northern China. 2019 Characterization of yuanbaofeng (Acer truncatum Bunge) samaras: Oil, fatty acid, and phytosterol content Ind. 112 301 307 doi: 10.1034/j.1399-3054.2001.1120301.x, Gao, J. WebTurf Center, Inc. 1409 Spencerville Road . 9:1286. doi: 10.1038/s41467-018-03421-7, Minciullo, P. L., Catalano, A., Mandraffino, G., Casciaro, M., Crucitti, A., Maltese, G., et al. DHA diet in the Sprague-Dawley rats increased the expression level of BDNF, which acted on TrkB receptor signaling to attenuate learning disability in rats (Wu et al., 2008). 188, 140154. They were differentiated by 0.5% hydrochloric acid ethanol for 10 s, and then rinsed with tap water for 10 min. 3 and 4), suggesting that they have an important role in UFA biosynthesis. 6 111 doi: 10.1038/s41438-019-0194-7, Wang, X.Y., Fan, J.S., Wang, S.Y. 4). To further investigate the reversal effect of acer truncatum seed oil on protein expression in the aging mice, we drew a Venn diagram and found that the seed oil reversed the expression of 44 proteins in the aging control, which also has differential expression compared to the young control (Figure 3D).